DNA Metabolism, Genomic Stability & Human Disease

Suzhou, China 
June 11-15, 2018   

Abstract deadline: April 20, 2018

Organized by:

Antony Carr, University of Sussex, UK

Daochun Kong, Peking University, China

Binghui Shen, Beckman Research Institute of the City of Hope, USA

Patrick Sung, Yale University, USA

Stephen West, The Francis Crick Institute, UK

We are pleased to announce the Cold Spring Harbor Asia conference on DNA Metabolism, Genomic Stability & Human Disease which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday June 11, and will conclude after lunch on June 15, 2018.

The conference will include eight oral sessions and one poster session covering the latest findings across many topics in DNA metabolism. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

Major Topics:
1. DNA replication & replication fork stability
2. Repair of DNA lesions
3. Chromatin structure & DNA metabolism
4. Genomic instability & disease

Keynote Speakers (Speaker, Affiliation, COUNTRY/Region）:
John Diffley, The Francis Crick Institute, United Kingdom
Abstract title: CDK misregulation inhibits loading of the replicative helicase to generate replicative stress
Marco Foiani, IFOM, ITALY
Abstract title: Abstract title: ATR controls nuclear mechanics and prevents nuclear collapse during interstitial migration
Lee Zou, MGH Cancer Center/Harvard Medical School, USA
Abstract title: Targeting the Aberrant R-Loop Accumulation in Cancer Cells with ATR Inhibitors

Invited Speakers (Speaker, Affiliation, COUNTRY/Region）:
Judith Campbell, California Institute of Technology, USA
Abstract title: Regulation of DNA2 nuclease/helicase by FANCD2
Antony Carr, University of Sussex, UNITED KINGDOM
Abstract title: Mechanisms of replication-associated genome rearrangement
Petr Cejka,Università della Svizzera italiana, SWITZERLAND
Abstract title: Mechanisms of DNA end resection: analysis of the Sae2 and Mre11-Rad50-Xrs2 nuclease complex
Junjie Chen, The University of Texas MD Anderson Cancer Center, USA
Abstract title: Regulation of DNA damage response and tumorigenesis
Jessica Downs, Institute of Cancer Research, UNITED KINGDOM
Abstract title: Loss of the PBAF chromatin remodelling complex leads to genome instability through multiple mechanisms
Vanesa Gottifredi, Fundación Instituto Leloir, ARGENTINA
Abstract title: Oncogenic and antioncogenic signals arising from the depletion of pol η in the Xeroderma Pigmentosum Variant disease
Eric Greene, Columbia University, USA
Daochun Kong, Peking University, China
Abstract title: Preventing uncoupling of replicative helicase and DNA polymerases is central for stabilization of stalling replication forks
Karim Labib, University of Dundee, United Kingdom
Abstract title: DESTROYING THE EUKARYOTIC REPLISOME
Gaëlle Legube, Université de Toulouse, UT3, FRANCE
Abstract title: Chromatin and Chromosome dynamics during DNA Double Strand break repair
Qing Li, Peking University, China
Abstract title: New insights into chromatin replication
Kristijan Ramadan, University of Oxford, UK
Abstract title: DNA-protein crosslinks (DPCs) proteolysis repair
Binghui Shen, Beckman Research Institute of the City of Hope, USA
Abstract title: Dynamic role of DNA2 in counteracting DNA replication stresses in human cells
Patrick Sung, Yale University School of Medicine, USA
Abstract title: Roles of the BRCA2-DSS1 complex in homology-directed DNA repair
Jesper Svejstrup, The Francis Crick Institute, UNITED KINGDOM
Abstract title: A ubiquitylation site in RNA Polymerase II that regulates the transcriptional response to UV damage
Stephen West, The Francis Crick Institute, UNITED KINGDOM
Abstract title: Unresolved recombination intermediates as a source of DNA breaks and chromosome aberrations
Xingzhi Xu, Shenzhen University, CHINA
Abstract title: UFMylation in the DNA damage response
Wei Yang, NIH Intramural Research Program, USA
Abstract title: Site-specific recombination in mammals
Yuxin Yin, Peking University, CHINA
Abstract title: PTEN family in genome stability and metabolism
Xiaolan Zhao, Memorial Sloan Kettering Cancer Center, USA
Abstract title: Elucidating DNA polymerase ε functions by modeling cancer-associated mutations

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers. 


Fellowship: 
We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $100-$500) awards. For more details, please visit Stipends

We look forward to seeing you at Suzhou in June, 2018.

Sponsored by:

Package Content:

Please kindly note:

1. Registration includes food, but does NOT include Housing. Due to requests from participants to provide more housing at lower prices, we have expanded our housing options to include some lower priced nearby hotels. After completing the online registration, you will receive a link to the full list of housing options.
*Reference Room Rate:
CNY 500 per standard room per night in the Conference Hotel (Worldhotel Grand Dushulake Suzhou)
Up from CNY 200 per standard room per night in nearby budget hotels (within 5 km)
CNY 400-700 per standard room per night in nearby 4-5 star hotels

2. The meeting registration is an integral package. We encourage all our participants to stay for the full meeting period and communicate with each other. No refund/discount or day pass is available for partial participation.

3. The early price will be available if the full payment is finished before the exact due date.
For USD participants, we will automatically change your package price to the update one if we could not successfully charge the payment from your registered credit card before the deadline.
For CNY participants, we will automatically change your package price to the update one if our bank account could not receive your full payment by wire transfer before the deadline.

4. For late registrations, your registration materials may not be guaranteed since the order is usually made in advance.

5. Please inform us your special request on food (vegetarian, kosher…etc.) or other things during the online registration or email us as early as possible so that we could make relevant arrangement accordingly.

6. Student package is exclusively designed for all the graduate, undergraduate and doctor students who have not received the doctor degree. (Student ID will be required upon arrival).

Currency converter