Membrane Proteins: from Physiology to Pharmacology

Suzhou, China 
May 6-10, 2019
Abstract deadline: March 15, 2019 

Schedule Overview

Conference Agenda

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Organized by:

Nancy Carrasco, Yale University, School of Medicine, USA

Baoliang Song, Wuhan University, China

Chris Tate, MRC Laboratory of Molecular Biology, UK

Nieng Yan, Princeton University, USA

We are pleased to announce the Cold Spring Harbor Asia conference on Membrane Proteins: from Physiology to Pharmacology which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday May 6, and will conclude after lunch on Friday.

The conference will include eight oral sessions and one poster session covering the latest findings across many topics in membrane proteins. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions. 

Major Topics:
1. Membrane excitability
2. Membrane proteins in signal transduction
3. Membrane transport
4. Lipid metabolism
5. Organelle dynamics
6. Membrane proteins and disease
7. Drug discovery

Keynote Speakers (Speaker, Affiliation, COUNTRY/Region):
Francisco Bezanilla, The University of Chicago, USA
Abstract title:Voltage sensor movement and its couplings to pore conductance 
Carol Robinson, University of Oxford, UK
Abstract title:From peripheral proteins to membrane motors – mass spectrometry comes of age. 

Invited Speakers (Speaker, Affiliation, COUNTRY/Region):
Christopher Ahern, University of Iowa Carver College of Medicine, USA
Abstract title:
Nancy Carrasco, Yale University, School of Medicine, USA
Abstract title:A non-transport oxyanion binding site allosterically controls the stoichiometry of the Na+/I- symporter (NIS)
Yuxing Chen, University of Science and Technology of China, CHINA
Abstract title:Structure of a MacAB-like efflux pump from Streptococcus pneumoniae
Mary Collins, The University of Sydney, AUSTRALIA
Abstract title:A functional genomic approach to identifying anti-epileptic agents targeting GABAA mutations
Karen Davies, The Babraham Institue, UNITED KINGDOM
Abstract title:Electron Cryo-Tomography of Mitochondria: The role of ATP Synthase in Shaping Cristae
Chris De Graaf, Sosei Heptares, UK
Abstract title:Structure-based drug design across the GPCRome
Hailan Hu, Zhejiang University, CHINA
Abstract title:Ion channel mechanisms underlying the rapid antidepressant effects of ketamine
Christophe Koth, Genentech, USA
Abstract title:The Molecular Basis for Selective Inhibition of the Pain-Associated Nav1.7 Sodium Channel
Wanda Kukulski, MRC Laboratory of Molecular Biology, UK
Abstract title:Architecture and function of organelle contact sites
Shengcai Lin, Xiamen University, CHINA
Abstract title:The ER-based transient receptor potential V channels are essential for glucose sensing by lysosomal aldolase and AMPK
Jen Liou, UT Southwestern Medical Center, USA
Abstract title:Inter-organelle signaling at membrane contact sites
Karin Reinisch, Yale School of Medicine, USA
Abstract title:VPS13 and VPS13-like proteins are lipid transporters.
Simon Scheuring, Weill Cornell Medicine, USA
Abstract title:High-Speed Atomic Force Microscopy: Real-Time Structural Dynamics of Unlabeled Membrane Proteins
Yigong Shi, Westlake University/Tsinghua University, China
Abstract title:Alzheimer’s disease, β-amyloid plaques, and γ-secretase
Baoliang Song, Wuhan University, CHINA
Abstract title:Cholesterol absorption, synthesis and beyond
Chris Tate, MRC Laboratory of Molecular Biology, UK
Abstract title:G protein-coupled receptors: the structural basis for high affinity agonist binding and G protein selectivity
Andrew Tobin, University of Glasgow, UK
Abstract title:Targeting the muscarinic receptor family in protection from neurodegenerative disease
Hongwei Wang, Tsinghua University, CHINA
Abstract title:
Ernest Wright, University of California, Los Angeles, USA
Abstract title:Sodium Glucose Symporters (SGLTs)
Beili Wu, Shanghai Institute of Materia Medica, CHINA
Abstract title:Structural basis of signal recognition and regulation at the full-length glucagon receptor
Xin Xie, Shanghai Institute of Materia Medica, CHINA
Abstract title:Targeting G protein-coupled receptors for the treatment of autoimmune diseases
Chenqi Xu, Institute of Biochemistry and Cell Biology, SIBS, CAS, CHINA
Abstract title:Decoding the phosphorylation program of T-cell receptor
Nieng Yan, Princeton University, USA
Abstract title:Molecular basis for the modulation of L-type voltage-gated Ca2+ channels by antagonistic and agonistic compounds
Hongyuan Yang, Universityof New South Wales, AUSTRALIA
Abstract title:The role of seipin in lipid droplet biogenesis
Litao Zhang, Bristol-Myers Squibb, USA
Abstract title:
Bei Zhang , Pfizer, USA
Abstract title:Modulations of circadian rhythm and urocortin 2 receptor signaling ameliorate hepatic steatosis and hyperinsulinemia 

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers. 

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $100-$500) awards. For more details, please visit

We look forward to seeing you at Suzhou in May, 2019.

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