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COLD SPRING HARBOR ASIA CONFERENCES


UBIQUITIN FAMILY, AUTOPHAGY & DISEASES

Presenting Author

Abstract Title

Talk/Poster

Behrends, Christian

Dissecting the contribution of autophagy to proteostasis by autophagosomal content profiling

talk

Chai, Qiyao

Ubiquitin targeting to Mycobacterium tuberculosis Rv1468c triggers the elimination of intracellular mycobacteria via host Atg5-dependent autophagy pathway

poster

Chen, Jo-Mei

The role and regulation of NF-κB during aggresome-autophagy formation

poster

Cheng, Jinke

Protein SUMOylation regulates metabolism

talk

Cheong, Jit Kong

Oncogenic RAS-induced CK1α drives nuclear FOXO Proteolysis

talk

Ciechanover, Aaron

Monoubiquitination as a novel proteasomal degradation signal—Mechanistic and biomedical implications

talk

Codogno, Patrice

Autophagy in organ integrity and in organ-to-organ communication

talk

de Thé, Hugues

Regulation of sumoylation by PML nuclear bodies upon oxidative stress

talk

Deak, Peter

Steady state levels of ubiquitin forms in Drosophila melanogaster

poster

Dikic, Ivan

Autophagy and ubiquitin networks in health and disease

talk

Dubiel, Hans Wolfgang

COP9 signalosome variants possessing CSN7A and CSN7B isoforms in adipogenesis

talk

Feng, Xin-hua

Control of canonical TGF-β signaling by ubiquitin and SUMO modifications

talk

Gao, Jiayang

Functional studies of exocyst positive organelle (expo) in plant

poster

Gupta, Neha

F-box protein FBXO24 functions as a novel regulator of APC/C complex

talk

Her, Lu-Shiun

The ubiquitin receptor ADRM1 mediates HAP40 overexpression-induced cellular defects

talk

Huang, Yun-Ru

Cdc42 mediates the coupled migration of centrosome and Golgi complex during directional cell migration

poster

Iwai, Kazuhiro

Mechanisms underlying the formation and stabilization of the LUBAC ligase complex

talk

Jia, LiJun

Transcriptional inactivation of estrogen receptor by neddylation inhibition sensitizes ER-positive breast cancer to fulvestrant

talk

Jin, Jianping

The roles of the CRL4 ubiquitin ligases in cellular signaling pathways

talk

Komatsu, Masaaki

Selective autophagy regulates lipid-oxidation through the NCoR1-PPARα axis

talk

Kuo, Shu-Ming

Inhibition of avian influenza A virus replication in human cells by host restriction factor TUFM is correlated with autophagy

talk

Kwon, Yong Tae

The N-end rule pathway mediates ER-phagy and regulates ER protein quality control via the p62-TRIM13 circuit

talk

Lai, Tung Faat

Structural and functional analysis of ATG9 by cryo-electron microscopy

poster

Lallemand-Breitenbach, Valerie

Regulation of sumoylation by PML NBs upon oxidative stress in vivo

talk

Lee, Byung-Hoon

Regulation of proteasome activity by ubiquitin chain editing

talk

Lee, Myung-Shik

Autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

talk

Li, Lihui

CRL3-BTBD9 targets TNFAIP1 for degradation and regulates cancer cell migration

talk

Li, Wei

Impaired autophagic flux in Leydig cells results in late-onset hypogonadism

talk

Li, Yanchang

LysargiNase coupled with trypsin digestion enhanced identification of protein ubiquitination sites

talk

Li, Yiming

A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation

poster

Li, Yi-Ping

E3 Ubiquitin ligase UBR2 is a key mediator of cancer-induced skeletal muscle protein loss

talk

Liao, Yi-Hao

The aggresome formation and subsequent autophagosome recruitment depend on modifications of alpha-tubulin

poster

Liu, Jinquan

Regulation of the TGF-β signaling pathway by the CRL4-AMBRA1 ubiquitin ligase via Smad4 ubiquitination

poster

Liu, Xiaoyan

Reversible phosphorylation of Rpn1 regulates 26S proteasome function

poster

Liu, Yaobin

Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination

talk

Luo, Li

Exercise preconditioning modulates autophagy/mitophagy and mitochondrial dynamics in a cerebral ischemic injury model of aged mice

poster

Luo, Qingyu

JOSD1 causes chemoresistance of ovarian cancer via stabilizing MCL1

poster

Luo, Zhao-Qing

Single protein-catalyzed ubiquitination—Mechanisms and implications in cell signaling

talk

Melchior, Frauke

A SUMO switch in EGF receptor signaling

talk

Nagy, Agota

Unique subunit composition of the Drosophila APC/C

poster

Pan, Lifeng

Mechanistic insight into the interactions of NAP1 with autophagy receptor NDP52 and TAX1BP1 for the recruitment of TBK1

talk

Piao, Hai-long

A multidimensional characterization of E3 Ubiquitin ligase and substrate interaction network

talk

Qiang, Lihua

Regulation of ubiquitin-proteasome pathway-dependent degradation of eEF1A1 by Mycobacterium tuberculosis Mce2E

poster

Qin, Wei

Quantitative time-resolved chemoproteomics reveals stable O-GlcNAc regulates box C/D snoRNP biogenesis

poster

Qiu, Xiaobo

Ubiquitination or acetylation-dependent protein degradation by proteasomes

talk

Rao, Feng

Small molecule-regulated deneddylation of Cullin Ring ubiquitin ligase 4 controls insulin secretion and weight gain

talk

Rao, Hai

How a DNA repair complex delivers p53 to the proteasome

talk

Ronai, Ze'ev

The ubiquitin ligase RNF5 controls melanoma growth by coordinated regulation of gut microbiota and anti-tumor activity

talk

Shao, Feng

Ubiquitination and degradation of GBPs by a Shigella effector to suppress host defense

talk

Sheng, Yi

HUWE1 missense mutation R2981H impairs E3 ligase function by disrupting the structure of a tandem ubiquitin-binding motif in XLID

talk

sohn, eun jung

MicroRNA 200c-3p regulates autophagy via upregulation of endoplasmic reticulum stress in PC- 3 cells

talk

Sun, Yi

Cross talks among three F-box proteins and two neddylation E2s

talk

Tan, Xianglong

Sortase-mediated chemical protein synthesis reveals the bidentate binding of bisphosphorylated p62 with K63 diubiquitin

poster

Tan, Xu

Proteomic and RNA-seq profiling of HIV infection in human CD4 T cells identifies a new ubiquitination target of HIV Vpu

talk

Tanaka, Keiji

Cell-mediated Immunity govern by immunoproteasome and thymoproteasome

talk

Tao, Yongguang

LncRNA GIAT4RA interferes with the degradation of LSH that enhances GINS4 mRNA stability

talk

Tsuchiya, Hikaru

Ub-ProT reveals global length and composition of protein ubiquitylation in cells

poster

Wan, Yong

Crosstalk between ubiquitylation and PARylation regulates KLF4-mediated genome stability and oncogenesis

talk

WANG, Chao

Potent and specific Atg8-targeting autophagy inhibitory peptides derived from giant ankyrins

talk

Wang, Chen

Regulating cytosolic DNA sensing by SUMO-specific protease 7

talk

Wang, Jing

Functions of COP9 signalosome variants containing CSN7A or CSN7B in AD293 cells

poster

Wang, Jing

The ubiquitin ligase TRIM27 functions as a host restriction factor against mycobacterial infection in vitro and in vivo

poster

Wei, Wenyi

Deficiency in SPOP-mediated ubiquitination and degradation of BRAF confers resistance to therapeutic BRAFV600E inhibitor

talk

WU, Hsin-Chieh

Actinomycin D selectively activates Trp53 in NPM1-mutant AML cells through PML-NBs reformation

poster

Wu, xiaowei

DUB3 attributes to chemoresistance of ovarian cancer by deubiquitinating MCL1

talk

Xie, Qi

The Arabidopsis 20S β5 subunit PBE1 is essential for intact 26S proteasome assembly under salt stress

talk

Xie, Xuan

Deubiquitinases USP5 and USP13 are recruited to and regulate heat-induced stress granules by deubiquitinating activities

poster

Yang, Bo

HMGB1 represses the anti-cancer activity of sunitinib by governing TP53 autophagic degradation via its nucleus-to-cytoplasm transport

talk

Ying, Meidan

Ubiquitin-dependent degradation of CDK2 drives the therapeutic differentiation of AML by targeting PRDX2

talk

YU, chuanyang

Structure and function studies of Arabidopsis ATG2-containing complexes by cryo-EM

poster

Yu, Li

Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation

talk

Yuan, Junying

Ubiquitination regulated RIPK1 activation controls apoptosis and necroptosis

talk

Zhang, Hong

Interaction of HECTD1, a HECT E3 ligase with APPL1 is critical for conversion of sorting endosomes to early endosomes and for epithelial-mesenchymal transition (EMT)

talk

Zhang, Hong

The ER-localized protein DFCP1 interacts with Seipin/BSCL2 to modulate ER-LD contact formation

talk

Zhang, Lingqiang

A Smurf1 tale—Function and regulation of an ubiquitin ligase in multiple cellular networks

talk

Zhang, Wenjuan

The Nedd8-activating enzyme inhibitor MLN4924 (TAK-924/Pevonedistat) induces apoptosis via c-Myc-Noxa axis in head and neck squamous cell carcinoma

poster

Zhang, Wenxin

Architecture of the plant exocyst complex by cryo-EM

poster

Zhang, Zihui

Testis-specific proteasome subunit α4s is required for meiosis and male fertility

poster

Zhao, Yuanbo

The regulation of degradation of TMEM208/hSnd2 by proline130

poster

Zheng, Hanqiu

A dual-luciferase based, genome-wide siRNA library screening identifies a novel E3 ubiquitin ligase for SNAI2 degradation in breast cancer metastasis

talk

Zhou, Lisha

Neddylation pathway promotes lung cancer metastasis by upregulating tumor-derived CCL2 to recruit M2-macrophages

poster

Zhu, Jingting

Autophagy induced by Simian retrovirus infection controls viral replication and apoptosis of Jurkat T kymphocytes

talk

Zou, Haojing

Identification of deubiquitinase that catalyzes KLF4 in genome stability and carcinogenesis

poster

 

 

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